QOMATROPIN (somatropin) 12MG 36IU CARTRIDGE.

• Recombinant human growth hormone somatropin (rDNA origin) for injection.
• Subcutaneous injection only.
• Mix gently.

Therapeutic Indications:-

Somatropin is advisable for a indelible treatment of children who possess growth disturbances due to the following conditions:-

• Short height/personality due to less secretion of pituitary growth hormone.
• Turner syndrome
• Chronic kidney disease
• Inherited small stature
• Prader Willi syndrome
• For replacement therapy

Recommended dosage:-

0.025 – 0.035 mg/kg body weight per day or 0.7 – 1.0 mg/m² body surface area per day. Even higher doses have been used.

Contraindications:-

• Hypersensitive patients to somatropin or any of its active ingredients.
• Patients or individuals who possess tumor cells.
• It should not be consumed by children with closed epiphyses.
• Patients with heart problems, those who suffered from stroke or kidney diseases.
• Patients who had surgeries.
• Accidental and trauma cases.

Drug Interactions:-

• Glucocorticoids:- it hinders the growth promoting action or effects of somatropin.
• Compounds which are metabolized by cytochrome P450 enzymes are cleared more rapidly by somatropin in individuals who are growth hormone deficient.

Use in Special Populations:-

Pregnancy:-

 Somatropin is not recommended or adviced in pregnant women or those who want to conceive as it may cause serious teratogenic effects in the fetus and can prove fatal for it. It should also be avoided in women who are under lactation period since it may get transferred to the feeding new born.

Mechanism of Action: QOMATROPIN (somatropin) 12MG 36IU CARTRIDGE.

Somatropin plays an essential role in the metabolism of proteins, lipids and carbohydrates.

It malnourished or stunted growth children it increases linear growth and also the rate of extension.

It increases body’s nitrogen retention which helps it in maintaining normal body composition in both children and adults.

It is incentive for skeletal muscle growth, and body fat mobilization. 

Most responsive tissue towards somatropin is visceral adipose tissue.

It also increases insulin like growth factor – I and insuling like growth factor binding protein 3. 

Uses: QOMATROPIN (somatropin) 12MG 36IU CARTRIDGE.

• It is used under following situations:- growth failure, growth hormone deficiency, intestinal disorder (short bowel syndrome) or HIV-related weight loss or wasting.
• Increases height in children.

Side effects: QOMATROPIN (somatropin) 12MG 36IU CARTRIDGE.

Headache, nausea, gagging, migraine vomiting,frazzle, tiredness, dizziness ,muscle pain, or weakness may occur. 

Tell your croaker right down if you have any serious side goods, including: nausea/vomiting that doesn’t stop, development of a limp, unusual tiredness, unusual/unexplained weight gain, cold wave doagmatism, frazzle, fast/slow heartbeat, ear pain/itching, hearing problems, hipsterism/knee pain, numbness/tingling, unusual increase in thirst or urination, swelling hands/ankle bases, change in the appearance or size of any operative, severe stomach/abdominal pain.

Get medical help right down if you have any veritably serious side goods including: vision problems/changes, seizure, severe headache.

Rare (conceively fatal) lung/breathing problems may be caused by this drug in children with Prader-Willi pattern. Those at advanced threat include males, operasively fat children, or those with serious lung/breathing problems ( such as sleep apnea, lung infections, lung complaint). Children should be checked for certain breathing problems (upper airway inhibition) before and during treatment. Tell the croaker right away if these signs do. 

Somatropin may increase your threat of excrescence or cancer. Discuss the details and the pitfalls and benefits of this drug with your croaker.

A veritable serious antipathetic response to this medicine is rare. However, get medical help right down if you notice any of the following symptoms of a serious antipathetic response: rash, itching/severe lump (especially of the face/lingo/throat), dizziness, trouble breathing.

Storehouse:-

Keep cooled between 2-8 °C.

Cover from sun

Keep it down from children