What is Semaglutide ?
Semaglutide is a medicine used to slim down in specific patients, as a hypoglycemia drug and also eliminates cardiovascular problems such as heart attack or stroke in type two diabetes patients thus it comes under the category of anti-diabetic medication and anti-obesity medication. It was developed by Novo Nordisk in 2012. It is a peptide analogue of GLP-1 with a modification in its side chain.
Route of administration:-
It can be administered orally or via a subcutaneous route through injection.
Mechanism of action of Semaglutide:-
It is a glucagon-like 1 peptide (GLP-1) agonist.
It increases the amount of insulin released from beta cells of pancreas and decreases the level of glucagon in the body.
Moreover, it delays emptying of the stomach and also reduces your appetite. When the stomach carries food for a greater time period, it sends signals of “fullness” to the brain.
The result of this process is an influential hunger subduing or vanquishing effect based on the patient’s own capacity to produce insulin. Patients don’t need to go through any surgeries or heavy medication in order to lose weight.
How much weight can you lose consuming semaglutide:-
Such medications must be consumed for at least a span of 3 months to see the desired benefits. It has been observed that 13 – 15 pounds of weight can be lost by using this medication for 3 months and 25- 27 pounds if consumed for 6 months. Thus on an average it can help you reduce at least 5 pounds in a month.
Uses :
- Controls sugar level of blood in type 2 diabetes patients.
- Decreases the risk of cardiovascular problems such as heart attack or strokes in patients prone to it.
- It promotes weight loss in patients who have an initial body mass index of 30kg/m2 or greater or patients who have a BMI of 27 kg/m2 or greater and also have at least one weight-related condition, such as hypertension, type 2 diabetes mellitus and lipidemia.
It is advised along with diet and exercise.
What must be avoided during its consumption?
According to studies, 2 things which must be avoided include foods containing fat like fried or greasy items and the other one is alcohol. You should also limit your sugar intake.
Side effects :
Less common –
- Chills
- Nausea, vomiting , fever.
- Pancreatitis (swelling of pancreas)
- Lightheadedness
- Constipation
- Recurrence of burp
- Bloated stomach ( feeling of full )
- Gastric pain
- Dyspepsia
- Hyperacidity
- Recurrent fever
- Yellow eyes or skin
- Indigestion
- Swelling and inflammation in stomach area
- Slight increase in levels of HDL.
Contraindications
- History of angioneurotic edema
- Medullary thyroid cancer
- multiple endocrine neoplasia syndrome type 2 (MEN 2)
- thyroid C-cell tumors
- Type 1 diabetes mellitus. …
- Hypoglycemia. …
- Pancreatitis. …
- Biliary lithiasis
- Diabetic retinopathy
- Renal failure, renal impairment
Does its usage affect your skin?
Ozempic face is the term used to denote the most common side effect it causes you which includes sagging and aging of facial skin.
Storage of semaglutide:
Store in the refrigerator. Do not freeze.
Store your new, unused medicine pen in its original carton in the refrigerator.
Avoid exposing it to extreme heat or cold as it may degrade the compound.
Moisture: Keep the medication away from moisture or humidity, as water can lead to chemical reactions that may alter its structure.
Out of Reach: Store semaglutide out of reach of children, pets, or anyone who should not have access to it.
Separation: Avoid storing semaglutide in the same location as food, beverages, or other medications to prevent cross-contamination.
Away from Airflow: Keep the substance away from fans, air conditioning vents, or other sources of strong airflow to prevent the dispersion of the compound.
